Specific studies evaluating pimobendan use in dogs with pre-clinical dilated cardiomyopathy and valvular heart disease with congestive heart failure provided invaluable information supporting the use of pimobendan in these specific patient populations. 7, 8, 9, 10 And now, decades after the first publications on pimobendan use were released, we finally have strong evidence supporting the use of pimobendan therapy in canine patients with pre-clinical valvular heart disease.
Pimobendan (brand name: Vetmedin) is a heart medication used to treat dogs with congestive heart failure (CHF), usually caused by either dilated cardiomyopathy or valvular insufficiency. Its use in cats to treat heart failure is ‘off label’ or ‘extra label’. Many drugs are commonly prescribed for off label use in veterinary medicine.
Pimobendan is approved for use in dogs to treat congestive heart failure originating from valvular insufficiency or dilated cardiomyopathy in some countries in Europe and in Canada, Mexico, and Australia and is currently undergoing Food and Drug Administration (FDA) review in the United States.
Vetmedin (pimobendan) Directions: Vetmedin is a prescription medication used in dogs to increase the ability of the heart to pump blood. Vetmedin is used for the management of mild, moderate, or severe congestive heart failure due to atrioventricular valvular insufficiency or dilated cardiomyopathy.
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However, the authors conclude that the improved outcome in dogs receiving pimobendan indicates that overall it is safe to give. The authors note that some dogs might have been incorrectly classified as having a cardiac (or noncardiac) cause for euthanasia or spontaneous death.
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In light of the findings, vets should now consider testing early for signs of preclinical MVD, and in dogs with cardiomegaly secondary to preclinical MVD, vets should consider the use of pimobendan to.
For dogs, the labeled dosage recommendation for pimobendan is 0.25 to 0.3 mg/ kg PO.. Pimobendan should not be used in dogs with ascites resulting from.
Pimobendan is a positive inotropic drug that is used to manage mild, moderate, or severe congestive heart failure in dogs and cats. It is particularly used in cases where the heart condition is caused by atrioventricular valvular insufficiency or dilated cardiomyopathy, because pimobendan causes the heart to pump blood more efficiently by opening the blood vessels that send and return blood.
A recent clinical trials shows that pimobendan delays the onset of congestive heart failure in dogs with mitral valve disease and cardiomegaly.